La Roche-Posay Effaclar Duo+M

Evidence-led ingredient analysis, a transparent clean score out of 100 and cleaner, effective alternatives at three price levels.

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La Roche-Posay

Effaclar Duo+M

Treatment · Budget: £20.90

4.5 (3,200 reviews)· across Boots UK, LookFantastic, Cult Beauty, La Roche-Posay UK

Verified against manufacturer INCI

Ingredients: Verified against manufacturer INCI

Last verified: 29 Aug 2026 · source

An effective blemish treatment combining niacinamide and salicylic acid, though undisclosed fragrance may irritate sensitive skin.

Hazard categories

88Safe / Clean
Safe / Clean88 · Safe / Clean ✓

Selenssa score out of 100

Formulation score is fixed across Selenssa · Community effectiveness awaiting more reports

Based on publicly available ingredients, following our methodology. Not medical advice — always check the physical label, especially for allergies. How we score →

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A highly effective spot and global blemish treatment for oily, breakout-prone skin, provided fragrance is tolerated.

Be cautious if

Users with extreme fragrance sensitivities or severe eczema should patch test before full application.

Against your clean standard

Meets clean standards for acne treatments, with minor deductions for undisclosed synthetic fragrance and ethoxylated emulsifiers.

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Where this score comes from

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Score history

No score changes have been recorded for this product yet.

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Does La Roche-Posay Effaclar Duo+M contain parabens, sulfates or fragrance?

A straight yes or no for the ingredient groups people most often want to avoid, checked against this product's published formulation.

  • Free from parabens

    Preservatives; the longer-chain ones (propyl, butyl) carry the endocrine questions.

  • Free from sulfates (sls / sles)

    Strong cleansing agents that can strip a compromised barrier.

  • Contains silicones

    Found: dimethicone. Slip and occlusion; cyclic silicones (D4/D5/D6) are the environmentally restricted ones.

  • Contains fragrance / parfum

    Found: parfum / fragrance. Undisclosed fragrance blends are the most common trigger for sensitised skin.

  • Free from essential oils

    Naturally derived, but among the most frequently reported contact allergens.

  • Free from drying alcohol

    Fine in small amounts for texture; high up the list it can dehydrate.

  • Free from formaldehyde releasers

    Preservatives that slowly release formaldehyde.

  • Free from chemical uv filters of concern

    Restricted or debated filters with endocrine or reef-persistence questions.

Is La Roche-Posay Effaclar Duo+M non-comedogenic?

No ingredients in this formulation appear on Selenssa's common pore-clogger list, so it is unlikely to be the cause of congestion for most people. Comedogenicity is still individual — texture, occlusion and how much you use all play a part.

Is La Roche-Posay Effaclar Duo+M safe for sensitive skin?

Usually tolerated, but patch test if your skin reacts easily.

  • Contains fragrance or parfum

Ingredients worth knowing about: Parfum / Fragrance.

Can you use La Roche-Posay Effaclar Duo+M while pregnant?

This product contains capryloyl salicylic acid, salicylic acid, which is usually on the list of ingredients people are advised to pause during pregnancy or breastfeeding. Selenssa is not medical advice — check with your midwife, GP or dermatologist before using it.

La Roche-Posay Effaclar Duo+M full ingredients list

12 ingredients analysed, in the order Selenssa assessed them. Concentration generally falls as you move down the list.

Aqua / Water / Eau, Glycerin, Dimethicone, Niacinamide, Zinc PCA, Capryloyl Salicylic Acid, Salicylic Acid, Vitreoscilla Ferment, 2-Oleamido-1,3-Octadecanediol, Poloxamer 338, Polysorbate 80, Parfum / Fragrance.

The actives doing the work: Niacinamide (Calms active redness while targetting post-blemish mark discoloration.); Salicylic Acid & LHA (Dual-action exfoliation unclogs pores without harsh physical scrubbing.); Zinc PCA (Balancing mineral that reduces excess surface shine and controls sebum.).

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